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Zanaflex (Tizanidine)Tizanidine (trade names include Zanaflex; Sirdalud; Ternelin; Tizan; Tizanidin Teva; Tizanidine Arrow; Tizanor; Tizpa) is a short-acting muscle relaxer from centrally acting muscle relaxants pharmacological group. This medicine is used for the treatment of muscle spasms, cramping, tightness of muscles caused by some diseases and medical conditions, such as spasticity, spastic diplegia, multiple sclerosis, amyotrophic lateral sclerosis (ALS), back pain, spinal cord injury, other injuries to the spine or CNS. It is also indicated to treat migraine headaches, some symptoms of fibromyalgia, as an anticonvulsant, as a sleep aid medication. Tizanidine HCl works by blocking nerve impulses (pain sensations) that are sent to your brain.

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Pharmaceutical forms and dosages:
  • Zanaflex (Tizanidine) 2 mg tablets
  • Zanaflex (Tizanidine) 4 mg tablets
  • Tizanidine Hydrochloride (Zanaflex) 2 mg tablets
  • Zanaflex 2 mg tablets
  • Zanaflex 4 mg tablets
  • Tizanidine 2 mg tablets
  • Tizanidine 4 mg tablets
  • Tizanidine (Zanaflex generic) 2 mg tablets
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  • Zanaflex 2 mg: 30, 60, 90, 120, 150, 180, 360 pills
  • Zanaflex 4 mg: 30, 60, 90, 120, 150, 180, 270, 360 pills
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  • Tizanidine Hydrochloride (Zanaflex) generic
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    There is an additional general information about Tizanidine (Zanaflex):


    Medical and pharmaceutical categories for tizanidine:

  • Alpha2-adrenergic agonists
  • Analgesics
  • Anti migraine medications
  • Anticonvulsants
  • Antispasmodics
  • Centrally acting skeletal muscle relaxants
  • Muscle relaxants
  • Pain relief drugs
  • Sleep aid pills


    The Anatomical Therapeutic Chemical (ATC) classification system tizanidine codes:

  • M - Musculo-skeletal system
  • M03 - Muscle relaxants
  • M03B - Muscle relaxants, centrally acting agents
  • M03BX - Other centrally acting agents
  • M03BX02 - Tizanidine


    Tizanidine in The International Statistical Classification of Diseases and Related Health Problems (ICD-10, World Health Organization) codes:

  • Amyotrophic lateral sclerosis - G12.21
  • Multiple sclerosis - G35
  • Epilepsy and recurrent seizures - G40
  • Migraine - G43
  • Sleep disorders - G47
  • Infantile cerebral palsy - G80
  • Spastic diplegic cerebral palsy - G80.1
  • Hemiplegia - G81
  • Paraplegia and tetraplegia - G82
  • Other diseases of spinal cord - G95
  • Dorsalgia - M54
  • Fibromyalgia - M79.7
  • Abnormal involuntary movements - R25
  • Injury of nerves and spinal cord at thorax level - S24


    Pregnancy categories for Tizanidine (Zanaflex):

  • C - Australia
  • C - United States (Risk cannot be ruled out)


    Salts and other tizanidine forms used as active pharmaceutical ingredients (API):

  • Tizanidine Base
  • Tizanidine Hydrochloride


    Synonyms of tizanidine, international and chemical names:

  • 2,1,3-Benzothiadiazole, 5-chloro-4-(2-imidazolin-2-ylamino)-
  • 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole
  • Tisanidine
  • Titsanidiini
  • Tizanidin
  • Tizanidina
  • Tizanidine HCL
  • Tizanidinhydrochlorid
  • Tinazidini Hydrochloridum
  • Tizanidinum
  • Tizanidyna


    Best known tizanidine brands, generics and trade names in various countries:

  • Apo-Tizanidine - Apotex
  • Flexitine - Behrens Laboratorio
  • Miorelax - Bioquifar Pharmaceutica
  • Movax - Sami Pharmaceuticals
  • Musant - Niche Generics
  • Musidin - Martin Dow Pharmaceuticals
  • Mylan-Tizanidine - Mylan
  • Myores - Meprofarm
  • Myos-Nor - Best Laboratorios
  • Phardex - Pharos Chemie
  • Sirdalud - Novartis
  • Sirdalud Retard - Novartis
  • Sirdalud-MR - Novartis; Dr. Reddy's Laboratories; Euro Registratie; Medcor Pharmaceuticals
  • Ternelax - Wander; Zuellig Pharma
  • Ternelin - Novartis; Sandoz
  • Tilax - Riyadh Pharma
  • Tinize - Genome Pharmaceuticals
  • Tizacom - Combiphar
  • Tizafen - Akros Pharma
  • Tizan - Sun Pharmaceutical Industries
  • Tizanidin - Actavis; Alternova; Orion Pharma; Teva
  • Tizanidina - Davur Laboratorios; Teva
  • Tizanidine - Actavis; Alphapharm; Arrow Pharmaceuticals; Eon Labs; Generics UK; Mylan; Sandoz; Teva
  • Tizanor - Orion Pharma
  • Tizpa - Blue Cross Laboratories; Gold Cross; S.J. & G. Fazul Ellahie
  • Zanaflex - Acorda Therapeutics


    Pharmaceutical active ingredients used in medicine in combinations with tizanidine:

  • Aceclofenac
  • Acetaminophen
  • Ciprofloxacin
  • Diclofenac
  • Ibuprofen
  • Mefenamic Acid
  • Nimesulide
  • Serrapeptase
  • Valdecoxib


    Some other medications in Zanaflex (Tizanidine) pharmacological classes:

  • Anabloc (Fenyramidol)
  • Benemid (Probenecid)
  • Buscopan (Butylscopolamine)
  • Colospa (Mebeverine)
  • Decontractil (Mephenesin)
  • Dulcolax (Bisacodyl)
  • Flexeril (Cyclobenzaprine)
  • Imigran (Sumatriptan)
  • Imitrex (Sumatriptan)
  • Imuran (Azathioprine)
  • Lioresal (Baclofen)
  • Lyseen (Pridinol)
  • Mestinon (Pyridostigmine)
  • MuscoRil (Thiocolchicoside)
  • Mydeton (Tolperisone)
  • Myolastan (Tetrazepam)
  • Myonal (Eperisone)
  • Nimotop (Nimodipine)
  • Parafon (Chlorzoxazone)
  • Pletal (Cilostazol)
  • Ponstel (Mefenamic Acid)
  • Probalan (Probenecid)
  • Relafen (Nabumetone)
  • Requip (Ropinirole)
  • Robaxin (Methocarbamol)
  • Savella (Milnacipran)
  • Skelaxin (Metaxalone)
  • Tegretol (Carbamazepine)
  • Voveran (Diclofenac Sodium)
  • Urispas (Flavoxate)


    Here is a list of some medications containing "Tizanidine" as a main component of tizanidine drugs, their trade names, available forms, doses and also pharmaceutical companies - manufacturers, distributors and suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Sirdalud
  • Tablets; Oral; Tizanidine Hydrochloride 1 mg
  • Tablets; Oral; Tizanidine Hydrochloride 2 mg
  • Tablets; Oral; Tizanidine Hydrochloride 4 mg
  • Tablets; Oral; Tizanidine Hydrochloride 6 mg
  • Novartis
  • DKSH
  • Dr. Reddy's Laboratories
  • Eurim-Pharm
  • Laus Farma
  • Paranova Danmark
  • San Giorgio Pharma
  • Sandoz
  • Sanofi-Aventis
  • Zuellig Pharma
  • Ternelin
  • Granules; Oral; Tizanidine Hydrochloride 2 mg / g
  • Tablets; Oral; Tizanidine Hydrochloride 1 mg
  • Tablets; Oral; Tizanidine Hydrochloride 2 mg
  • Tablets; Oral; Tizanidine Hydrochloride 4 mg
  • Novartis
  • Sandoz
  • Tizan
  • Tablets; Oral; Tizanidine 2 mg
  • Tablets; Oral; Tizanidine 4 mg
  • Sun Pharmaceutical Industries
  • Pharmaland
  • Sin Phyu Kyun Company
  • Tizanidin-Teva
  • Tablets; Oral; Tizanidine Hydrochloride 2 mg
  • Tablets; Oral; Tizanidine Hydrochloride 4 mg
  • Tablets; Oral; Tizanidine Hydrochloride 6 mg
  • Teva
  • Tizanor
  • Tablets; Oral; Tizanidine Hydrochloride 2 mg
  • Tablets; Oral; Tizanidine Hydrochloride 4 mg
  • Orion Pharma
  • Zanaflex
  • Capsules; Oral; Tizanidine Hydrochloride 2 mg
  • Capsules; Oral; Tizanidine Hydrochloride 4 mg
  • Capsules; Oral; Tizanidine Hydrochloride 6 mg
  • Tablets; Oral; Tizanidine Hydrochloride 2 mg
  • Tablets; Oral; Tizanidine Hydrochloride 4 mg
  • Acorda Therapeutics
  • Cephalon
  • Elan Pharmaceuticals
  • Paladin Laboratories
  • Shire
  • Squire Pharmaceuticals
  • Zeneus Pharma


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